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Singular Genomics G4™ Sequencing Platform

Next-gen benchtop DNA sequencer.

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About

Research

Design

UI/UX

Branding

Engineering

Outcomes
Researchers and clinicians grappled with bulky, slow, and inflexible sequencers. Singular Genomics aimed to deliver unprecedented throughput, intuitive operation, and plug‑and‑play integration—without compromising scientific precision or compact lab footprint. RKS Design

Turning high-stakes genomics into seamless lab workflows

Client

Singular Genomics

Markets

Life Science
Commercial

What We Did

Industrial Design
Product Engineering
Product Development
Psycho-Aesthetics®
Branding Design
A large, modern genomic sequencing machine with a black and silver design sits on a laboratory counter, with trees visible through large windows in the background.
RKS engaged deeply with genomics researchers, technicians, and lab managers to map operational pain points—workflow inefficiencies, setup complexity, and cognitive load during high-throughput tasks. Using Psycho‑Aesthetics®, we placed G4 in the artistic quadrant—balancing technical power with emotional clarity and environmental integration.

Research Insights & Discovery

KEY OUTPUTS

Lab workflow and persona mapping 

Emotional journey insights
Benchmarking
Opportunity Areas & Design Criteria

How We Used Psycho-Aesthetics™ to Identify Unique Opportunities in the Project.

Using our proprietary Psycho-Aesthetics® 2.0 framework, we conducted in-depth interviews and ethnographic observation in diverse lab settings. We identified key emotional and usability pain points — such as intimidation with complex interfaces, workspace clutter, and trust in precision. These insights guided both the form and interface strategy, ensuring approachability and confidence in operation.

PA Map of RKS Design's project with Singular Genomics.
A presentation slide showing personas, features like error reduction, feedback types, product benchmarking with an Illumina HiSeq 3000, and design concepts with modular and detail sketches.
We engineered a compact, sculptural chassis with modular access panels and integrated status lighting. The tower-like form allows front-side consumable access (sample cartridges, SBS reagents, flow cells) and emphasizes visual clarity in labs.

Industrial Design Concept Development

KEY OUTPUTS

CAD studies optimizing bench footprint
CMF Strategy
Refined Industrial Design Language
Singular G4 Product Design Attributes
Singular Genomics Consumable sketches
Close-up view of four black microscope slide holders with blue accents inside a high-tech Singular Genomics laboratory device, possibly for automated slide scanning or analysis.
The user interface guides scientists through setup, status monitoring, sequencing, and export with minimal navigation. Visual feedback and status illumination simplify real-time diagnostics and reduce cognitive load.

UI/UX Design Development

KEY OUTPUTS

Information Architecture
Touchscreen Interface Design
Custom Iconography & Visual System
Interactive Prototypes
Side Angle Hero Shot of Singular Genomics DNA Sequencer designed by RKS Design
We established a modern identity system—logo, typography, lighting treatments, and messaging—that communicates innovation, academic credibility, and approachable technology, supporting early-stage investor and user adoption.

Branding Design

KEY OUTPUTS

Cohesive visual identity aligned with brand and product values
Marketing visuals
A modern office building with large glass windows displays the Singular Genomics logo, showcasing thoughtful branding design. In front, a sign reads Singular Genomics and Alexandria 3010, surrounded by greenery and trees.
Singular Logo Guidelines Product Design
Singular Branding Guidelines Product Design
Singular Branding Guidelines Product Design
Collaborating closely with Singular’s internal teams, engineers developed fluidics integration, cartridge mechanisms, thermal architecture, and optical imaging stacks. The result: a highly calibrated, repeatable sequencing instrument.

Product Engineering & Development

KEY OUTPUTS

Functional engineering prototypes
CAD/CAM deliverables optimized for manufacturing and maintenance
Reliability testing and thermal performance validation
Singular Prototype Product Design
Singular Genomics G4™ exemplifies RKS Design’s ability to elevate complex instrumentation through human-centered design. By harmonizing high-performance sequencing chemistry with emotional design clarity, lab integration, and brand elevation, we delivered a platform that empowers scientists to accelerate discovery without compromise. The modular G4X expansion further cements the platform’s leadership in next-gen and spatial multiomics. Let me know if you’d like to include scientist testimonials, funding narrative, or comparative performance charts.

Key Outcomes and Results

Key Accomplishments

Seamless compatibility with established sample prep kits.

Singular Genomics secured over $294M in funding aligned to the G4 platform.
Wide adoption across oncology, immunology, and research settings globally.

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