EVOS M5000 Imaging System

Compact automated cell imaging system.

Fluent cell imaging often required bulky, complex microscopes and extensive operator training. Thermo Fisher aimed to offer a productivity-enhancing solution featuring automation, intuitive operation, and a sleek form that improves bench-space efficiency without sacrificing imaging quality.

Lab-grade imaging, simplified

ThermoFisher Evos5000, designed by RKS Design, fully integrated digital benchtop microscope
We conducted on-site lab field studies to track preferences, pain points, and divergent workflows. Technicians expressed frustration with manual focus, limited lab space, and inconsistent imaging. RKS used our Psycho‑Aesthetics® model to define a system experience that balanced confidence, ease, and spatial harmony.

Research Insights & Discovery

KEY OUTPUTS

User Personas
Psycho-Aesthetics® 2.0 Map
Benchmarking
Opportunity Areas & Design Criteria

How We Used Psycho-Aesthetics™ to Identify Unique Opportunities in the Project.

Using our proprietary Psycho-Aesthetics® 2.0 framework, we conducted in-depth interviews and ethnographic observation in diverse lab settings. We identified key emotional and usability pain points — such as intimidation with complex interfaces, workspace clutter, and trust in precision. These insights guided both the form and interface strategy, ensuring approachability and confidence in operation.

PA Map of RKS Design's project with ThermoFisher
A grid of 15 presentation slides featuring diagrams, charts, personas, processes, and text, showing various business concepts like benchmarks, journeys, and workflows with a white background and red and gray accents.
RKS designed a streamlined chassis—compact enough to fit on busy lab benches yet roomy enough to house motorized optics and filters. Clear access hatches, self-calibrating trays, and integrated lighting zones were designed for visibility and intuitiveness. Attention to detail is evident in every aspect of the design, from the carefully selected materials to the intuitive interface.

Industrial Design Concept Development

KEY OUTPUTS

CAD iterations optimizing volume, airflow, and user reach
Functional mock-ups highlighting sample tray insertion and calibration lids
DFM guidelines ensuring serviceability and kit consistency
Thermo Fisher Detail Shots Product Design
ThermoFisher Visual Essay Process Image/Sketches 2
We coordinated closely with Thermo Fisher engineers to integrate optics, motorized stage mechanisms, and computational modules. RKS ensured proper alignment, thermal performance, and structural stability for reproducible imaging. From its easy self-installation to advanced color options and Thermo Fisher Connect™ connectivity, the EVOS M5000 microscope is designed for optimal performance and convenience.

Engineering Validation

KEY OUTPUTS

Prototypes with precision sample trays, filter wheels, and autofocus
Service documentation, materials specification, and calibration protocols
Thermal and component tests validating uptime and imaging fidelity
ThermoFisher Visual Essay Product Collage 1
The result of RKS Design’s collaboration on this project is an exceptional laboratory microscope that meets the demands of modern research. Its biosafety cabinet compatibility and the integration of the EVOS Onstage Incubator allow for live-cell analysis with precise control over temperature, humidity, and gases. One of the standout features of the EVOS M5000 microscope is its advanced color options, which enable users to capture user-defined four-color fluorescence, transmitted light, and color images. The EVOS M5000 Imaging System represents the perfect blend of industrial design, functionality, and innovation, providing researchers with a versatile and user-friendly laboratory microscope.

Key Outcomes and Results

Key Accomplishments

EVOS M5000 is actively sold and integrated worldwide as part of Thermo Fisher’s benchtop cell-imaging portfolio.
Lab technicians report significant gains in workflow speed
Product harmonizes design language across the EVOS line, strengthening brand clarity and customer trust
A person operates a Thermo Fisher EVOS M5000 digital microscope while a monitor displays green-stained cell images. Colorful microscopic images are visible on the wall in the background.

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